CX-516
CX-516 ,aslo known as BDP 12 and SPD-420, is an ampakine and nootropic that acts as an AMPA receptor positive allosteric modulator. It was researched as a treatment for Alzheimer's disease under the brand name Ampalex, and was also being examined as a treatment for ADHD. CX-516 showed good in vitro activity and positive results in animal tests, the human trials proved disappointing due mainly to low potency and short half-life. However, CX-516 is still widely used in animal research into the ampakine drugs and is the standard reference compound that newer, more potent drugs of this class such as farampator and CX-717 are compared to.
Supplier | Ace Therapeutics |
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Product # | SMD1474 |
CAS # | 154235-83-3 |
Pricing | Customizable size, Inquiry |
Synonym | CX-516; CX 516; CX516; BDP 12; BDP-12; BDP12; SPD-420; SPD420; brand name: Ampalex. |
Product Category | Lab-use Small Molecule Drugs |
Chemical Formula | C14H15N3O |
Exact Mass | 241.1215 |
Molecular Weight | 241.294 |
Elemental Analysis | C, 69.69; H, 6.27; N, 17.41; O, 6.63 |
IUPAC/Chemical Name | 1-(quinoxalin-6-ylcarbonyl)piperidine |
InChi Key | ANDGGVOPIJEHOF-UHFFFAOYSA-N |
InChi Code | InChI=1S/C14H15N3O/c18-14(17-8-2-1-3-9-17)11-4-5-12-13(10-11)16-7-6-15-12/h4-7,10H,1-3,8-9H2 |
SMILES Code | O=C(N1CCCCC1)C2=CC=C3N=CC=NC3=C2 |
Appearance | Solid powder |
Purity | >98% (or refer to the Certificate of Analysis) |
Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
Solubility | Soluble in DMSO, not in water |
Shelf Life | >2 years if stored properly |
Drug Formulation | This drug may be formulated in DMSO |
Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
HS Tariff Code | 2934.99.9001 |
Availability | 2 Weeks |