DMT-2'-O-TBDMS-G(dmf)-CE Phosphoramidite

DMT-2'-O-TBDMS-G(dmf)-CE Phosphoramidite is a specialized nucleotide used in oligonucleotide synthesis. It features a dimethoxytrityl (DMT) protecting group on the 3' hydroxyl, a tert-butyldimethylsilyl (TBDMS) protecting group on the 2' hydroxyl, and a guanine base modified with a dimethylformamide (dmf) group. Additionally, it contains a 5'-cyanoethyl (CE) phosphoramidite functionality for controlled addition during synthesis. This compound enables stable and precise synthesis of oligonucleotides for various molecular biology research applications, including gene silencing, antisense therapy, and diagnostics.

• Supplier: BOC Sciences
• Product #: BRP-00402
• Cas: 149559-87-5
• Molecular Weight: 955.18
• Molecular Formula: C49H67N8O8PSi
• Canonical SMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1O[Si](C)(C)C(C)(C)C)N2C=NC3=C2N=C(NC3=O)N=CN(C)C)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC