15-Deoxy-Δ-12,14-prostaglandin J2

Supplier MedChemExpress
Product # HY-108568
CAS # 87893-55-8
Pricing inquire
Biological Activity 15-Deoxy-Δ-12,14-prostaglandin J2 (15d-PGJ2) is a cyclopentenone prostaglandin and a metabolite of PGD2. 15-Deoxy-Δ-12,14-prostaglandin J2 is a selective PPARγ (EC50 of 2 µM) and a covalent PPARδ agonist. 15-Deoxy-Δ-12,14-prostaglandin J2 promotes efficient differentiation of C3H10T1/2 fibroblasts to adipocytes with an EC50 of 7 μM[1][2].
Synonyms 15d-PGJ2; 15-Deoxy-Δ12,14-PGJ2
MWt 316.43
Formula C₂₀H₂₈O₃
Feedback