Fostamatinib disodium hexahydrate
Supplier | MedChemExpress |
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Product # | HY-13038B-50 mg |
CAS # | 914295-16-2 |
Pricing | 50 mg, USD $432.0 |
Biological Activity | Fostamatinib (R788) disodium hexahydrate is the oral prodrug of the active compound R406[1]. R406 is an orally available and competitive Syk/FLT3 inhibitor with a Ki of 30 nM and an IC50 of 41 nM[2]. R406 also inhibits Lyn (IC50=63 nM) and Lck (IC50=37 nM)[3]. |
Synonyms | R788 disodium hexahydrate |
MWt | 732.51 |
Formula | C₂₃H₃₆FN₆Na₂O₁₅P |