9-Decyn-1-ol
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-130985 |
| CAS # | 17643-36-6 |
| Pricing | inquire |
| Biological Activity | 9-Decyn-1-ol is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs. 9-Decyn-1-ol can be used to conjugate GDC-0068 with Lenalidomide to generate INY-03-041. INY-03-041 is a potent, highly selective and PROTAC-based pan-Akt degrader. INY-03-041 inhibits Akt1, Akt2 and Akt3 with IC50s of 2.0 nM, 6.8 nM and 3.5 nM, respectively[1]. |
| MWt | 154.25 |
| Formula | C₁₀H₁₈O |