Tos-PEG4-t-butyl ester

Supplier MedChemExpress
Product # HY-130422-10 mM * 1 mL
CAS # 217817-01-1
Pricing 10 mM * 1 mL, USD $55.0
Biological Activity Tos-PEG4-t-butyl ester (Tos-PEG4-Boc) is a PROTAC linker, which refers to the PEG composition. Tos-PEG4-t-butyl ester (Tos-PEG4-Boc) can be used in the synthesis of a series of PROTACs, such as BI-3663 (HY-111546). BI-3663 is a highly selective PTK2/FAK PROTAC, with cereblon ligands to hijack E3 ligases for PTK2 degradation, and inhibits PTK2 with an IC50 of 18 nM[1].
Synonyms Tos-PEG4-Boc
MWt 432.53
Formula C₂₀H₃₂O₈S
Feedback