INCA-6
INCA-6, a cell-permeable quinone compound, is a selective and potent inhibitor of Calcineurin Nuclear Factor of Activated T cells (NFAT) signaling. It binds to calcineurin with high affinity and does not affect calcineurin activity or its downstream signaling. It blocks its dephosphorylation and nuclear import, thus interferes with downstream targets of NFAT including induction of cytokine mRNAs.
| Supplier | BOC Sciences |
|---|---|
| Product # | 3519-82-2 |
| Pricing | Inquire |
| Cas | 3519-82-2 |
| Molecular Weight | 284.31 |
| Molecular Formula | C20H12O2 |
| Canonical SMILES | C1=CC=C2C3C4=CC=CC=C4C(C2=C1)C5=C3C(=O)C=CC5=O |