D-I03
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-124691-5 mg |
| CAS # | 688342-78-1 |
| Pricing | 5 mg, USD $80.0 |
| Biological Activity | D-I03 is a selective RAD52 inhibitor with a Kd of 25.8 µM. D-I03 specifically inhibits RAD52-dependent single-strand annealing (SSA) and D-loop formation with IC50s of 5 µM and 8 µM, respectively. D-I03 suppresses growth of BRCA1- and BRCA2-deficient cells and inhibits formation of damage-induced RAD52 foci, but does not effect on RAD51 foci induced by Cisplatin[1][2]. |
| Purity | ≥98.0% |
| MWt | 428.64 |
| Formula | C₂₃H₃₆N₆S |