TAK-960 hydrochloride
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-15160A |
| CAS # | 1137868-96-2 |
| Pricing | inquire |
| Biological Activity | TAK-960 hydrochloride is an orally available, selective inhibitor of polo-like kinase 1 (PLK1), with an IC50 of 0.8 nM. TAK-960 hydrochloride also shows inhibitory activities against PLK2 and PLK3, with IC50s of 16.9 and 50.2 nM, respectively. TAK-960 hydrochloride inhibits proliferation of multiple cancer cell lines and exhibits significant efficacy against multiple tumor xenografts[1]. |
| MWt | 598.06 |
| Formula | C₂₇H₃₅ClF₃N₇O₃ |