SK1-I hydrochloride
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-119016A-50 mg |
| CAS # | 2366222-05-9 |
| Pricing | 50 mg, USD $1700.0 |
| Biological Activity | SK1-I hydrochloride (BML-258 hydrochloride), an analog of sphingosine, is an isozyme-specific competitive SPHK1 inhibitor with a Ki value of 10 µM[1]. SK1-I hydrochloride shows no activity at SPHK1 PKCα, PKCδ, PKA, AKT1, ERK1, EGFR, CDK2, IKKβ or CamK2β. SK1-I hydrochloride enhances autophagy and has antitumor activity[2]. |
| Synonyms | BML-258 hydrochloride |
| MWt | 313.86 |
| Formula | C₁₇H₂₈ClNO₂ |