Recombinant Human Anti-IAV HA Antibody (CT149)
Recombinant Human Antibody (CT149) is capable of binding to IAV HA, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-IAV HA mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-IAV HA mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition. This antibody is found to neutralize all tested group 2 and some group 1 influenza A viruses by inhibiting low pH-induced, HA-mediated membrane fusion.
| Supplier | Creative Biolabs |
|---|---|
| Product # | PABL-213 |
| Pricing | Inquiry |
| Host | Human |
| Target | IAV HA |
| Species Reactivity | IAV |
| Type | IgG |
| Applications | Can be useful in applications such as: Western blot; Neutralization; Functional Study |
| Storage | Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples. |