KDM5A-IN-1
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-100014-100 mg |
| CAS # | 1905481-36-8 |
| Pricing | 100 mg, USD $2520.0 |
| Biological Activity | KDM5A-IN-1 is a potent, orally bioavailable pan-histone lysine demethylases 5 (KDM5) inhibitor with IC50s of 45 nM, 56 nM and 55 nM for KDM5A, KDM5B and KDM5C, respectively, and with an EC50 value of 960 nM for PC9 H3K4Me3. KDM5A-IN-1 is significantly less potent against other KDM5B enzymes (1A, 2B, 3B, 4C, 6A, 7B)[1]. |
| Purity | 98.41% |
| MWt | 290.36 |
| Formula | C₁₅H₂₂N₄O₂ |