Human Anti-CD18 Recombinant Antibody (clone H52)
Recombinant Humanized Antibody (H52) is capable of binding to CD18, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-CD18 mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-CD18 mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition. The humanization of the anti-CD18 antibody H52 was hampered by not appreciating the possibilitythat residues in the C-terminal part of CDR-H2could be important in antigen binding.
| Supplier | Creative Biolabs |
|---|---|
| Product # | PABZ-019 |
| Pricing | Inquiry |
| Host | Human |
| Target | CD18 |
| Species Reactivity | Human |
| Type | Human IgG |
| Applications | FC |
| Storage | Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles. |