DH4
DH4 is a SERT inhibitor with IC50 = 0.58 nM. DH4 was discovered with a bioavailability of 83.28% in rats by replacing the nonbioavailable substructure of approved drug vilazodone. DH4 exhibits promising antidepression efficacy in animal experiments.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD800 |
| CAS # | N/A |
| Pricing | Customizable size, Inquiry |
| Synonym | DH4; DH 4; DH-4 |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C26H24F2N6 |
| Exact Mass | 458.2 |
| Molecular Weight | 458.52 |
| Elemental Analysis | C, 68.11; H, 5.28; F, 8.29; N, 18.33 |
| IUPAC/Chemical Name | 3-(3-(4-(5-(2,4-difluorophenyl)pyrimidin-2-yl)piperazin-1-yl)propyl)-1H-indole-5-carbonitrile |
| InChi Key | MONCKXMZFAXBAZ-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C26H24F2N6/c27-21-4-5-22(24(28)13-21)20-16-31-26(32-17-20)34-10-8-33(9-11-34)7-1-2-19-15-30-25-6-3-18(14-29)12-23(19)25/h3-6,12-13,15-17,30H,1-2,7-11H2 |
| SMILES Code | FC1=CC(F)=CC=C1C(C=N2)=CN=C2N(CC3)CCN3CCCC4=CNC5=CC=C(C#N)C=C54 |
| Appearance | To be determined |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | To be determined |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | To be determined |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |