GR 127935 HCl
GR 127935 HCl is a potent and selective 5-HT1B/1D receptor antagonist (pKi values are 8.5 for both guinea pig 5-HT1D and rat 5-HT1B receptors). GR 127935 HCl displays > 100-fold selectivity over 5HT1A, 5-HT2A, 5-HT2C receptors and other receptor types.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD859 |
| CAS # | 148642-42-6 |
| Pricing | Customizable size, Inquiry |
| Synonym | GR 127935; GR-127935; GR 127935 HCl; GR 127935. |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C29H32ClN5O3 |
| Molecular Weight | 534.057 |
| Elemental Analysis | C, 65.22; H, 6.04; Cl, 6.64; N, 13.11; O, 8.99 |
| IUPAC/Chemical Name | N-[4-Methoxy-3-(4-methyl-1-piperazinyl)phenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-1,1'-biphenyl-4-carboxamide hydrochloride |
| InChi Key | SRVVUYIJVBLEJI-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C29H31N5O3.ClH/c1-19-17-23(28-30-20(2)37-32-28)9-11-25(19)21-5-7-22(8-6-21)29(35)31-24-10-12-27(36-4)26(18-24)34-15-13-33(3)14-16-34;/h5-12,17-18H,13-16H2,1-4H3,(H,31,35);1H |
| SMILES Code | O=C(C1=CC=C(C2=CC=C(C3=NOC(C)=N3)C=C2C)C=C1)NC4=CC=C(OC)C(N5CCN(C)CC5)=C4.[H]Cl |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Availability | 2 Weeks |