Decitabine
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-A0004-10 mM * 1 mL |
| CAS # | 2353-33-5 |
| Pricing | 10 mM * 1 mL, USD $66.0 |
| Biological Activity | Decitabine (NSC 127716) is an orally active deoxycytidine analogue antimetabolite and a DNA methyltransferase inhibitor. Decitabine incorporates into DNA in place of cytosine can covalently trap DNA methyltransferase to DNA causing irreversible inhibition of the enzyme. Decitabine induces cell G2/M arrest and cell apoptosis. Decitabine has potent anticancer activity[1][2]. |
| Synonyms | 5-Aza-2'-deoxycytidine; 5-AZA-CdR; NSC 127716 |
| MWt | 228.21 |
| Formula | C₈H₁₂N₄O₄ |