Decitabine

Supplier MedChemExpress
Product # HY-A0004-10 mM * 1 mL
CAS # 2353-33-5
Pricing 10 mM * 1 mL, USD $66.0
Biological Activity Decitabine (NSC 127716) is an orally active deoxycytidine analogue antimetabolite and a DNA methyltransferase inhibitor. Decitabine incorporates into DNA in place of cytosine can covalently trap DNA methyltransferase to DNA causing irreversible inhibition of the enzyme. Decitabine induces cell G2/M arrest and cell apoptosis. Decitabine has potent anticancer activity[1][2].
Synonyms 5-Aza-2'-deoxycytidine; 5-AZA-CdR; NSC 127716
MWt 228.21
Formula C₈H₁₂N₄O₄
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