L-745870 trihydrochloride
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-14325A |
| CAS # | 866021-03-6 |
| Pricing | inquire |
| Biological Activity | L-745870 trihydrochloride is a potent, selective, brain-penetrant and orally active dopamine D4 receptor antagonist with a Ki of 0.43 nM. L-745870 trihydrochloride shows weaker affinity for D2 (Ki of 960 nM) and D3 (Ki of 2300 nM) receptors, and exhibits moderate affinity for 5-HT2 receptors, sigma sites and α-adrenoceptors[1][2][3]. |
| MWt | 436.21 |
| Formula | C₁₈H₂₂Cl₄N₄ |