Cys(Npys) Antennapedia Peptide, amide

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Product # X21212
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MolecularWeight 2503.1
Sequence
  • One Letter Code: C(Npys)-RQIKIWFQNRRMKWKK-NH2
  • Three Letter Code: H-C(Npys)Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-NH2
Storage -20°C
Explanation This is the 16 amino acid region of Antennapedia peptide (Penetratin) synthesized with an activated cysteine residue C(Npys), wherein Npys is 3-Nitro-2-pyridinesulfenyl group is used for activating S of cysteine and for rapid reaction when a thiol group is introduced. This kind of modification has been used to render this peptide as a carrier peptide applicable in conjugation studies, especially when studying attachment of peptide-like molecules to carriers.
Reference Hodoniczky J. et al. Pep Sci. 90(5):595-603(2008).
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