Aurora kinase inhibitor-3

Supplier MedChemExpress
Product # HY-112373-1 mg
CAS # 879127-16-9
Pricing 1 mg, USD $90.0
Biological Activity Aurora kinase inhibitor-3 is a strong and selective Aurora A kinase inhibitor with an IC50 of 42 nM, and weakly inhibits EGFR with an IC50 of >10 μM. Aurora kinase inhibitor-3 has a binding mode with the cyclopropanecarboxylic acid moiety directed towards the solvent exposed region of the ATP-binding pocket[1].
Purity 98.98%
MWt 413.4
Formula C₂₁H₁₈F₃N₅O
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