Human Anti-HNE Recombinant Antibody (clone R310)
Recombinant Human Antibody (R310) is capable of binding to HNE, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-HNE mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-HNE mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition. This antibody showed only a slight crossreactivity with the native double-stranded DNA, whereas the Ab immunoreactivity was dramatically enhanced by the treatment of the DNA with 4-oxo-2-nonenal (ONE), an analog of HNE.
| Supplier | Creative Biolabs |
|---|---|
| Product # | PABL-197 |
| Pricing | Inquiry |
| Host | Human |
| Target | HNE |
| Type | Human IgG |
| Applications | WB, ELISA, FuncS |
| Storage | Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles. |