EGFR-IN-1
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-19617 |
| CAS # | 1625677-63-5 |
| Pricing | inquire |
| Biological Activity | EGFR-IN-1 (compound 24) is an orally active and irreversible L858R/T790M mutant selective EGFR inhibitor. EGFR-IN-1 potently inhibits Gefitinib-resistant EGFR L858R, T790M with 100-fold selectivity over wild-type EGFR. EGFR-IN-1 displays strong antiproliferative activity against the H1975 cells and the first line mutant HCC827 cells. Antitumor activity[1]. |
| MWt | 514.58 |
| Formula | C₂₈H₃₀N₆O₄ |