Phospho-Erk1/2 Antibody
| Supplier | CD BioSciences |
|---|---|
| Product # | AMA-0231 |
| Pricing | 100 µg, Inquire |
| Product Category | Antibodies |
| Application | WB, IHC |
| Product Usage Information Dilution | Western Blotting (0.5-4 µg/ml); Immunoprecipitation (10-20 µg/mL); Immunohistochemistry (10-20 µg/mL) |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Gene ID | 116590 |
| Source/Isotype | Rabbit IgG |
| Storage | Store at -20°C. |
| Purification | Affinity purified |
| Background | Both p44 and p42 MAP kinases (Erk1 and Erk2) function in a protein kinase cascade that plays a critical role in the regulation of cell growth and differentiation. Activation of MAP kinases occurs throμgh phosphorylation of threonine and tyrosine (202 and 204 of human MAP kinase [Erk1] or 183 and 185 of rat Erk2) at the sequence T*EY* by a single upstream MAP kinase kinase (MEK). Both kinases are known to weakly autophosphorylate on tyrosine. |