Infigratinib (BGJ398)
Infigratinib (BGJ398) is a potent and selective FGFR inhibitor for FGFR1/2/3 with IC50 of 0.9 nM/1.4 nM/1 nM in cell-free assays, >40-fold selective for FGFR versus FGFR4 and VEGFR2, and little activity to Abl, Fyn, Kit, Lck, Lyn and Yes. Phase 2.
Supplier | Selleck Chemicals |
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Product # | S2183 |
Sku # | S2183-25mg |
Pricing | 25mg, $270.00 |
Citations for this product:
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bioRxiv - Systems Biology 2019Quote: ... 5 μM BGJ398 (NVP-BGJ398) (S2183, Selleck Chemicals) in Std medium ...