Mutated EGFR-IN-3

Supplier MedChemExpress
Product # HY-130608
CAS # 2375107-27-8
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Biological Activity Mutated EGFR-IN-3 (compound 3) is a potent, ATP-competitive and highly selective allosteric dibenzodiazepinone inhibitor of the EGFR(L858R/T790M) and EGFR(L858R/T790M/C797S) mutants with IC50 values of 12 nM and 13 nM, respectively[1].
MWt 508.59
Formula C₃₁H₂₉FN₄O₂
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