Afuco™ Anti-Human MET ADCC Therapeutic Antibody (ABT-700), ADCC Enhanced
Anti-MET ADCC Enhanced Antibody (ABT-700) is an ADCC enhanced antibody produced by our Afuco™ platform. ABT-700 is an anti-c-Met antibody with significant preclinical single-agent activity against MA human xenograft tumors. ABT-700 was well tolerated and appeared to have substantial single-agent activity. In this small cohort of gastric patients MA appears to be more common in treatment-refractory tumors than in primary untreated tumors, suggesting that screening efforts should focus on this treatment-refractory patient population.
| Supplier | Creative Biolabs |
|---|---|
| Product # | AFC-501CL |
| Pricing | Inquiry |
| Host | Humanized |
| Target | MET |
| Species Reactivity | Human |
| Type | ADCC enhanced antibody |
| Storage | Store at -20°C for long-term storage. Store at 4°C for up to one month. Avoid freeze/thaw cycles. |