Usmarapride
Usmarapride, also known as SUVN-D4010, is a potent, selective, brain penetrant and orally active 5-HT4 receptor partial agonist for the treatment of cognitive dysfunction associated with Alzheimer’s disease and other dementias. Suven submitted Investigational New Drug Application (IND) to US FDA to conduct Phase-1 clinical trial for Cognition in Alzheimer’s Disease. SUVN-D4010 may be potentially useful for treating Alzheimer’s disease, cognitive disorders, Attention deficit hyperactivity disorder, Parkinson’s and schizophrenia
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD1741 |
| CAS # | 1428862-32-1 |
| Pricing | Customizable size, Inquiry |
| Synonym | SUVN-D4010; SUVN-D 4010; SUVN D4010; SUVN-1004028; SUVN-D-1208045; SUVN-D1003019; SUVN-D1104010; SUVN-D1108121; usmarapride |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | 383.4960 |
| Exact Mass | 383.2321 |
| Molecular Weight | 0.0 |
| Elemental Analysis | C, 65.77; H, 7.62; N, 18.26; O, 8.34 |
| IUPAC/Chemical Name | 2-(1-isopropyl-1H-indazol-3-yl)-5-(1-(3-methoxypropyl)piperidin-4-yl)-1,3,4-oxadiazole |
| InChi Key | DWTFBJGTRBMHPG-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C21H29N5O2/c1-15(2)26-18-8-5-4-7-17(18)19(24-26)21-23-22-20(28-21)16-9-12-25(13-10-16)11-6-14-27-3/h4-5,7-8,15-16H,6,9-14H2,1-3H3 |
| SMILES Code | COCCCN1CCC(C2=NN=C(C3=NN(C(C)C)C4=C3C=CC=C4)O2)CC1 |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO, not in water |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |