Astemizole
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-12532-10 mM * 1 mL |
| CAS # | 68844-77-9 |
| Pricing | 10 mM * 1 mL, USD $55.0 |
| Synonyms | R 43512 |
| MWt | 458.57 |
| Formula | C₂₈H₃₁FN₄O |
| Biological Activity | Astemizole (R 43512), a second-generation antihistamine drug to diminish allergic symptoms with a long duration of action, is a histamine H1-receptor antagonist, with an IC50 of 4 nM. Astemizole also shows potent hERG K+ channel blocking activity with an IC50 of 0.9 nM. Astemizole has antipruritic effects[1][2]. |
| Purity | ≥98.0% |