Anti-Human LGR5 Therapeutic Antibody (BNC101)
Recombinant Humanized monoclonal antibody expressed in CHO binding to Human LGR5. BNC101 is a humanized monoclonal antibody targeting LGR5, that has demonstrated functional activity against Cancer Stem Cells (CSCs) from primary colorectal cancer (CRC) patient samples. In preclinical studies, BNC101 significantly reduces CSC frequency in vivo and prevents tumour re-growth in long term studies. BNC101 also increases survival and inhibits weight loss in a cachexic CRC tumour model. To date BNC101 has shown no evidence of toxicity in preliminary safety analyses.
| Supplier | Creative Biolabs |
|---|---|
| Product # | TAB-490CL |
| Pricing | Inquiry |
| Type | Antibody |
| Storage | Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage. |
| Target | LGR5 |
| Species Reactivity | Human |