Lofepramine
Lofepramine is a first generation tricyclic antidepressant. Lofepramine is a serotonin and noradrenaline re-uptake inhibitor (SNRI) that is metabolized to desipramine (sc-200158, sc-207535). Lofepramine produces inhibition of liver tryptophan pyrollase activity in vitro.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD968 |
| CAS # | 23047-25-8 |
| Pricing | Customizable size, Inquiry |
| Synonym | Lofepramine; HSDB 7184; Amplit; LEO 640; Lofepraminum; Lopramine; |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C26H27ClN2O |
| Exact Mass | 418.1812 |
| Molecular Weight | 418.965 |
| Elemental Analysis | C, 74.54; H, 6.50; Cl, 8.46; N, 6.69; O, 3.82 |
| IUPAC/Chemical Name | 4'-Chlor-2-((3-(10,11-dihydro-5H-dibenz(b,f)azepin-5-yl)propyl)methylamino)acetophenon |
| InChi Key | SAPNXPWPAUFAJU-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C26H27ClN2O/c1-28(19-26(30)22-13-15-23(27)16-14-22)17-6-18-29-24-9-4-2-7-20(24)11-12-21-8-3-5-10-25(21)29/h2-5,7-10,13-16H,6,11-12,17-19H2,1H3 |
| SMILES Code | O=C(C1=CC=C(Cl)C=C1)CN(CCCN2C3=CC=CC=C3CCC4=CC=CC=C42)C |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Availability | 2 Weeks |