PIK-75 hydrochloride
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-13281-100 mg |
| CAS # | 372196-77-5 |
| Pricing | 100 mg, USD $204.0 |
| Biological Activity | PIK-75 hydrochloride is a reversible DNA-PK and p110α-selective inhibitor, which inhibits DNA-PK, p110α and p110γ with IC50s of 2, 5.8 and 76 nM, respectively. PIK-75 hydrochloride inhibits p110α >200-fold more potently than p110β (IC50=1.3 μM)[1][2]. PIK-75 hydrochloride induces apoptosis[3]. |
| Purity | ≥98.0% |
| MWt | 488.74 |
| Formula | C₁₆H₁₅BrClN₅O₄S |