L-006235
Supplier | MedChemExpress |
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Product # | HY-103352-100 mg |
CAS # | 294623-49-7 |
Pricing | 100 mg, USD $1150.0 |
Synonyms | L-235 |
MWt | 466.6 |
Formula | C₂₄H₃₀N₆O₂S |
Biological Activity | L-006235 (L-235) is a potent, selective, reversible and orally active inhibitor of cathepsin K, with an IC50 of 5 nM in bone resorption assay. L-006235 shows selectivity for cathepsin K (Ki=0.2 nM) over cathepsin B, cathepsin L, and cathepsin S (Ki=1, 6, and 47 μM, respectively). L-006235 can reduce collagen degradation and prevent bone loss[1][2]. |
Purity | 98.03% |