A-317491 sodium salt hydrate

Supplier MedChemExpress
Product # HY-15568A-50 mg
Pricing 50 mg, USD $617.0
Biological Activity A-317491 sodium salt hydrate is a potent, selective and non-nucleotide antagonist of P2X3 and P2X2/3 receptors, with Kis of 22, 22, 9, and 92 nM for hP2X3, rP2X3, hP2X2/3, and rP2X2/3, respectively. A-317491 sodium salt hydrate is highly selective (IC50>10 μM) over other P2 receptors and other neurotransmitter receptors, ion channels, and enzymes. A-317491 sodium salt hydrate reduces inflammatory and neuropathic pain by blocking P2X3 and P2X2/3 receptor-mediated calcium flux[1][2].
Purity 99.65%
MWt 606.57
Formula C₃₃H₂₉NNaO₉
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