Bilanafos-sodium
Bialaphos is a natural non-selective phytotoxin produced by certain Streptomyces species. It is a pro-toxin, a tripeptide that is converted in vivo to the active agent phosphinothricin, which is a glutamine analog. L-Phosphinothricin inhibits glutamine synthetase (Ki = 6.1 µM), resulting in accumulation of ammonium and disruption of primary metabolism. The bacterial bar gene encodes a phosphinothricin acetyltransferase, which confers resistance to phosphinothricin.3 Bialaphos is used in the selection of transgenic plants that express the bar gene, usually under the control of a constitutively active viral promoter.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD1411 |
| CAS # | 71048-99-2 |
| Pricing | Customizable size, Inquiry |
| Synonym | Bilanafos-sodium; MW 801; SF 1293; Bialaphos sodium; |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C11H21N3NaO6P |
| Molecular Weight | 345.26 |
| Elemental Analysis | C, 38.27; H, 6.13; N, 12.17; Na, 6.66; O, 27.80; P, 8.97 |
| IUPAC/Chemical Name | sodium (2-amino-4-((hydroxymethyl)hydrophosphoryl)butanoyl)-L-alanyl-L-alaninate |
| InChi Key | ABIKTJOYXWTPDS-NKGRROCASA-M |
| InChi Code | InChI=1S/C11H22N3O6P.Na/c1-6(9(16)14-7(2)11(18)19)13-10(17)8(12)3-4-21(20)5-15;/h6-8,15,21H,3-5,12H2,1-2H3,(H,13,17)(H,14,16)(H,18,19);/q;+1/p-1/t6-,7-,8?;/m0./s1 |
| SMILES Code | C[C@@H](C([O-])=O)NC([C@H](C)NC(C(N)CCP(CO)=O)=O)=O.[Na+] |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Availability | 2 Weeks |