Human Anti-HLA-B27 Recombinant Antibody (clone HD5); scFv Fragment
Provided is an antibody, which binds to HLA-B27 heavy-chain homodimers, termed HC-B27, HLA-B272 or B272, particularly recognizing B272 homodimers and which does not recognize or bind HLA-B27 heterotrimers (B27) including HLA-B27 heterotrimers with β2 microglobulin and peptide. The antibody is useful in the diagnosis and treatment of HLA-B27 mediated conditions, particularly those associated with B272, the spondylarthritides, a group of related diseases including ankylosing spondylitis (AS) and reactive arthritis (ReA or Reiter's syndrome).
| Supplier | Creative Biolabs |
|---|---|
| Product # | HPAB-J0121-YC-S(P) |
| Pricing | Inquiry |
| Host | Human |
| Target | HLA-B27 |
| Species Reactivity | Human |
| Type | Human scFv |
| Applications | ELISA, FC |
| Storage | Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles. |