Galanin (2-11) (AR-M 1896)

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Supplier	Creative Peptides
Product #	R1888
CAS #	367518-31-8
Pricing	Inquire
MolecularFormula	C54H81N13O14
MolecularWeight	1136.3
Sequence	One Letter Code: WTLNSAGYLL Three Letter Code: H-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-NH2
Storage	-20 °C or below
ShippingCondition	RT, or blue ice upon request.
Explanation	Galanin is a 29-aa neuropeptide with a complex role in pain processing. Galanin receptor subtypes are present in dorsal root ganglia and spinal cord with a differential distribution. Three galanin receptors, GalR1, GalR2, and GalR3, have been identified and cloned. AR-M1896 is a specific galanin R2 (GalR2) agonist.
InChI	InChI=1S/C54H81N13O14/c1-26(2)17-37(46(57)73)62-49(76)38(18-27(3)4)63-51(78)40(20-31-13-15-33(70)16-14-31)61-44(72)24-59-47(74)29(7)60-53(80)42(25-68)66-52(79)41(22-43(56)71)64-50(77)39(19-28(5)6)65-54(81)45(30(8)69)67-48(75)35(55)21-32-23-58-36-12-10-9-11-34(32)36/h9-16,23,26-30,35,37-42,45,58,68-70H,17-22,24-25,55H2,1-8H3,(H2,56,71)(H2,57,73)(H,59,74)(H,60,80)(H,61,72)(H,62,76)(H,63,78)(H,64,77)(H,65,81)(H,66,79)(H,67,75)/t29-,30+,35-,37-,38-,39-,40-,41-,42-,45-/m0/s1
InChIKey	SUJPPMXJCZETOA-ZKEPBWIVSA-N
CanonicalSMILES	CC(C)CC(C(=O)N)NC(=O)C(CC(C)C)NC(=O)C(CC1=CC=C(C=C1)O)NC(=O)CNC(=O)C(C)NC(=O)C(CO)NC(=O)C(CC(=O)N)NC(=O)C(CC(C)C)NC(=O)C(C(C)O)NC(=O)C(CC2=CNC3=CC=CC=C32)N
Solubility	Soluble to 1 mg/ml in 20% formic acid
IsomericSMILES	C[C@H]([C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N)NC(=O)[C@H](CC2=CNC3=CC=CC=C32)N)O
Purity	≥97% by HPLC

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