PF-06372865
PF-06372865, also known as Darigabat, is a potent α2/3/5 subunit selective GABAa positive allosteric modulator.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD344 |
| CAS # | 1614245-70-3 |
| Pricing | Customizable size, Inquiry |
| Synonym | PF06372865; PF 06372865; PF-06372865; Darigabat |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C22H21FN4O3S |
| Exact Mass | 440.1318 |
| Molecular Weight | 440.49 |
| Elemental Analysis | C, 59.99; H, 4.81; F, 4.31; N, 12.72; O, 10.90; S, 7.28 |
| IUPAC/Chemical Name | 7-Ethyl-4-(4'-(ethylsulfonyl)-6-fluoro-2'-methoxybiphenyl-3-yl)-7H-imidazo[4,5-c]pyridazine |
| InChi Key | PTTQXDBPTFOCMT-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C22H21FN4O3S/c1-4-27-13-24-21-18(12-25-26-22(21)27)14-6-9-19(23)17(10-14)16-8-7-15(11-20(16)30-3)31(28,29)5-2/h6-13H,4-5H2,1-3H3 |
| SMILES Code | COC1=CC(S(=O)(CC)=O)=CC=C1C2=C(F)C=CC(C3=C4C(N(CC)C=N4)=NN=C3)=C2 |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >3 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |