R406 free base
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-11108-10 mM * 1 mL |
| CAS # | 841290-80-0 |
| Pricing | 10 mM * 1 mL, USD $158.0 |
| Biological Activity | R406 free base is an orally available and competitive Syk/FLT3 inhibitor for ATP binding with a Ki of 30 nM, potently inhibits Syk kinase activity in vitro with an IC50 of 41 nM, measured at an ATP concentration corresponding to its Km value. R406 free base reduces immune complex-mediated inflammation[1]. R406 free base also inhibits Lyn (IC50=63 nM) and Lck (IC50=37 nM)[2]. |
| Purity | 99.69% |
| MWt | 470.45 |
| Formula | C₂₂H₂₃FN₆O₅ |