Mouse Mavs Antibody
Required for innate immune defense against viruses. Acts downstream of DDX58 and IFIH1/MDA5, which detect intracellular dsRNA produced during viral replication, to coordinate pathways leading to the activation of NF-kappa-B, IRF3 and IRF7, and to the subsequent induction of antiviral cytokines such as IFN-beta and RANTES (CCL5). May activate the same pathways following detection of extracellular dsRNA by TLR3. May protect cells from apoptosis (By similarity).
Supplier | Abbexa Ltd. |
---|---|
Product # | abx031371-80UL |
Pricing | 80 µl USD $326.25 |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Host | Rabbit |
Tested Applications | ELISA, WB |
UniProt Primary AC | Q8VCF0 |
Dry Ice | No |
Availability | Shipped within 5-10 working days. |
Note | This product is for research use only. |