Mouse Anti-GD2 Recombinant Antibody (clone 7A4)
A antibody directed against GD2 (7A4) was cloned, sequenced, and expressed. Its binding properties were characterized and compared to that of the parental mab 7A4. The 7A4 bound to GD2+ neuroblastoma cell lines but not to GD2- cell lines or to GD2- cells isolated from peripheral blood. ELISA and thin-layer chromatography (TLC) indicated that it retained the anti-GD2 specificity, and exhibited a slight cross-reaction with GD3 as the parental mab. This antibody makes it possible to develop new useful reagents through genetic engineering for adjuvant tumor therapy.
| Supplier | Creative Biolabs |
|---|---|
| Product # | FAMAB-0126YC |
| Pricing | Inquiry |
| Host | Mouse |
| Target | GD2 |
| Species Reactivity | Human |
| Type | Mouse IgG3, κ |
| Applications | ELISA |
| Storage | Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles. |