20(S)-Hydroxycholesterol

Supplier MedChemExpress
Product # HY-12316-10 mM * 1 mL
CAS # 516-72-3
Pricing 10 mM * 1 mL, USD $231.0
Synonyms 20α-Hydroxycholesterol
MWt 402.65
Formula C₂₇H₄₆O₂
Biological Activity 20(S)-hydroxyCholesterol (20α-Hydroxycholesterol) is an allosteric activator of the oncoprotein smoothened (Smo) that activates the hedgehog (Hh) signaling pathway with an EC50 of 3 μM in a gene transcription reporter assay using NIH3T3 cells[1][2].
Purity ≥98.0%
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