Venlafaxine HCl
Venlafaxine is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class. Venlafaxine is usually categorized as a serotonin-norepinephrine reuptake inhibitor (SNRI), but it has been referred to as a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI). It works by blocking the transporter "reuptake" proteins for key neurotransmitters affecting mood, thereby leaving more active neurotransmitters in the synapse. The neurotransmitters affected are serotonin and norepinephrine. Additionally, in high doses it weakly inhibits the reuptake of dopamine, with recent evidence showing that the norepinephrine transporter also transports some dopamine as well, since dopamine is inactivated by norepinephrine reuptake in the frontal cortex.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD499 |
| CAS # | 99300-78-4 (HCl) |
| Pricing | Customizable size, Inquiry |
| Synonym | Wy-45030; Wy45030; Wy 45030; Venlafaxine HCl. brand names: Effexor, Effexor XR, Lanvexin, Viepax and Trevilor. |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C17H28ClNO2 |
| Molecular Weight | 313.866 |
| Elemental Analysis | C, 65.06; H, 8.99; Cl, 11.29; N, 4.46; O, 10.19 |
| IUPAC/Chemical Name | 1-[2-(dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexan-1-ol hydrochloride |
| InChi Key | QYRYFNHXARDNFZ-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C17H27NO2.ClH/c1-18(2)13-16(17(19)11-5-4-6-12-17)14-7-9-15(20-3)10-8-14;/h7-10,16,19H,4-6,11-13H2,1-3H3;1H |
| SMILES Code | OC1(C(C2=CC=C(OC)C=C2)CN(C)C)CCCCC1.[H]Cl |
| Appearance | White to off-white crystalline powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO, not in water |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Class-2 | Depression |
| Availability | 2 Weeks |