DLK-IN-1

Supplier MedChemExpress
Product # HY-114331-10 mg
CAS # 1620574-24-4
Pricing 10 mg, USD $850.0
Biological Activity DLK-IN-1 is a selective, orally active inhibitor of dual leucine zipper kinase (DLK, MAP3K12), with a Ki of 3 nM. DLK-IN-1 retains excellent CNS penetration and is well tolerated following multiple days of dosing at concentrations that exceed those required for DLK inhibition in the brain. DLK-IN-1 has activity in a model of Alzheimer’s Disease.
Purity 99.47%
MWt 423.43
Formula C₂₀H₂₄F₃N₅O₂
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