PROTAC CDK2/9 Degrader-1
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-130709-5 mg |
| CAS # | 2408641-24-5 |
| Pricing | 5 mg, USD $750.0 |
| Biological Activity | PROTAC CDK2/9 Degrader-1 (Compound F3) is a potent dual degrader for CDK2 (DC50=62 nM) and CDK9 (DC50=33 nM). PROTAC CDK2/9 Degrader-1 suppresses prostate cancer PC-3 cell proliferation (IC50=0.12 µM) by effectively blocking the cell cycle in S and G2/M phases. PROTAC CDK2/9 Degrader-1 is a PROTAC by tethering CDK inhibitor with CRBN ligand[1]. |
| Purity | 98.40% |
| MWt | 815.84 |
| Formula | C₄₀H₄₁N₁₃O₇ |