BI-9321
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-114208 |
| CAS # | 2387510-86-1 |
| Pricing | inquire |
| Biological Activity | BI-9321 is a potent, selective and cellular active nuclear receptor-binding SET domain 3 (NSD3)-PWWP1 domain antagonist with a Kd value of 166 nM. BI-9321 is inactive against NSD2-PWWP1 and NSD3-PWWP2. BI-9321 specifically disrupts histone interactions of the NSD3-PWWP1 domain with an IC50 of 1.2 μM in U2OS cells[1]. |
| MWt | 360.43 |
| Formula | C₂₂H₂₁FN₄ |