N-Desmethyltamoxifen hydrochloride

Supplier MedChemExpress
Product # HY-129099A-50 mg
CAS # 15917-65-4
Pricing 50 mg, USD $950.0
Biological Activity N-Desmethyltamoxifen hydrochloride is the major metabolite of tamoxifen in humans. N-Desmethyltamoxifen, a poor antiestrogen, is a ten-fold more potent protein kinase C (PKC) inhibitor than Tamoxifen. N-Desmethyltamoxifen hydrochloride is also a potent regulator of ceramide metabolism in human AML cells, limiting ceramide glycosylation, hydrolysis, and sphingosine phosphorylation[1][2][3].
Purity 99.62%
MWt 393.95
Formula C₂₅H₂₈ClNO
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