Cys(Npys)-TAT (47-57), FAM-labeled

Supplier Creative Peptides
Product # GR1227
Pricing Inquire
MolecularWeight 2302.7
Sequence Cys(Npys) -Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Lys(FAM)-NH2
Storage -21°C
Explanation This is a peptide corresponds to the protein transduction domain of the TAT protein and is synthesized with an activated cysteine residue C(Npys), wherein Npys is 3-Nitro-2-pyridinesulfenyl group and is used for activating S of cysteine and for rapid reaction when a thiol group is introduced. This is synthesized with C(Npys) at the N-terminus for applications requiring specific conjugation reactions and has a fluorophore labeled with FAM having Abs/Em=494/518 nm. This kind of modification has been used to render this peptide as a cell penetrating and carrier peptide applicable in conjugation studies.
Solubility Soluble in water for a solution up to 2 mg/ml, otherwise acetonitrile is recommend. Avoid repeated freezing and thawing.
Feedback