O-Desmethyl Midostaurin
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-129491-5 mg |
| CAS # | 740816-86-8 |
| Pricing | 5 mg, USD $1600.0 |
| Biological Activity | O-Desmethyl Midostaurin (CGP62221; O-Desmethyl PKC412) is the active metabolite of Midostaurin (HY-10230) via cytochrome P450 liver enzyme metabolism. O-Desmethyl Midostaurin can be used as an indicator for Midostaurin metabolism in vivo[1]. Midostaurin is a multi-targeted protein kinase inhibitor with IC50 ranging from 22-500 nM. |
| Synonyms | CGP62221; O-Desmethyl PKC412 |
| MWt | 556.61 |
| Formula | C₃₄H₂₈N₄O₄ |