N-Desmethylclozapine
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-G0021-10 mM * 1 mL |
| CAS # | 6104-71-8 |
| Pricing | 10 mM * 1 mL, USD $106.0 |
| Synonyms | Norclozapine; Desmethylclozapine; Normethylclozapine |
| MWt | 312.8 |
| Formula | C₁₇H₁₇ClN₄ |
| Biological Activity | N-Desmethylclozapine is a major active metabolite of the atypical antipsychotic drug Clozapine. N-Desmethylclozapine is a potent, allosteric and partial M1 receptors agonist (EC50=115 nM) and is able to potentiate hippocampal N-methyl-d-aspartate (NMDA) receptor currents through M1 receptor activation. N-Desmethylclozapine is also a δ-opioid agonist[1][2]. |
| Purity | 99.72% |