DS-1205b free base
DS-1205b free base, a potent and selective AXL kinase inhibitor with an IC50 of 1.3 nM, inhibits cell migration in vitro and tumor growth in vivo. It also inhibits MER, MET and TRKA with IC50s of 63, 104 and 407 nM, respectively.
Supplier | BOC Sciences |
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Product # | 1855860-24-0 |
Pricing | Inquire |
Cas | 1855860-24-0 |
Molecular Weight | 735.80 |
Molecular Formula | C41H42FN5O7 |
Canonical SMILES | CC1=CN=C(C=C1)C2=CN(C=C(C2=O)C(=O)NC3=CC(=C(C=C3)C4=C(N=CC(=C4)C5=CC(=C(C=C5)OCC6COCCO6)OC)N)F)CC7CCOCC7 |