A-485
A-485 is a potent, selective and drug-like p300/CBP catalytic inhibitor with an IC50 of 0.06 μM for p300 HAT. It is selective over BET bromodomain proteins and >150 non-epigenetic targets.
| Supplier | Selleck Chemicals |
|---|---|
| Product # | S8740 |
| Sku # | S8740-2mg |
| Pricing | 2mg, $197.00 |
Citations for this product:
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bioRxiv - Molecular Biology 2024Quote: ... CBP/p300 KAT inhibition was performed by adding 3 uM A-485 (Selleck Chemicals, S8740) as in57 for 30 minutes prior to doxycycline addition ...
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bioRxiv - Cancer Biology 2022Quote: ... MLN4924 (#S7109) and A-485 (#S8740) were purchased from Selleck Chemical. CPI-1205 and UNC1999 were synthesized as previously reported(39,40) ...